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Western Blot (WB) (Western blot analysis of Cathepsin V expression in Jurkat (Lane 1) and mouse small intestine (Lane 2) lysate.)

Rabbit Cathepsin V Polyclonal Antibody | anti-CTSV antibody

Cathepsin V antibody

Gene Names
CTSV; CTSU; CATL2; CTSL2
Applications
Western Blot
Purity
Cathepsin V antibody was purified by affinity chromatography
Synonyms
Cathepsin V; Polyclonal Antibody; Cathepsin V antibody; Polyclonal Cathepsin V; anti-Cathepsin V; CTSV; MGC125957; CTSU; CTSL2; CATL2; CATL 2; anti-CTSV antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Cathepsin V antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
334
Applicable Applications for anti-CTSV antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
Cathepsin V, also known as Cathepsin L2 and Cathepsin U, is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
Cathepsin V antibody was raised in Rabbit using synthetic peptide surrounding amino acid 21 of human Cathepsin as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Cathepsin V expression in Jurkat (Lane 1) and mouse small intestine (Lane 2) lysate.)

Western Blot (WB) (Western blot analysis of Cathepsin V expression in Jurkat (Lane 1) and mouse small intestine (Lane 2) lysate.)
Related Product Information for anti-CTSV antibody
Rabbit polyclonal Cathepsin V antibody
Product Categories/Family for anti-CTSV antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
37,329 Da
NCBI Official Full Name
cathepsin V
NCBI Official Synonym Full Names
cathepsin V
NCBI Official Symbol
CTSV
NCBI Official Synonym Symbols
CTSU; CATL2; CTSL2
NCBI Protein Information
cathepsin L2
UniProt Protein Name
Cathepsin L2
UniProt Gene Name
CTSV
UniProt Synonym Gene Names
CATL2; CTSL2; CTSU
UniProt Entry Name
CATL2_HUMAN

NCBI Description

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Uniprot Description

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.

Protein type: Protease; EC 3.4.22.15; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q22.2

Cellular Component: lysosomal lumen; extracellular space; neuron projection; microvillus; apical part of cell; nucleolus; extracellular region; perikaryon; external side of plasma membrane; secretory granule

Molecular Function: protein binding; histone binding; cysteine-type endopeptidase activity; protein complex binding; aminopeptidase activity; kininogen binding; cysteine-type carboxypeptidase activity; peptide binding; cysteine-type peptidase activity

Biological Process: extracellular matrix organization and biogenesis; hair follicle morphogenesis; response to glucocorticoid stimulus; Sertoli cell differentiation; multicellular organismal aging; antigen processing and presentation of exogenous peptide antigen via MHC class II; decidualization; cellular response to starvation; proteolysis; extracellular matrix disassembly; protein autoprocessing; response to glucose stimulus; autophagic cell death; nerve development; spermatogenesis

Research Articles on CTSV

Similar Products

Product Notes

The CTSV ctsv (Catalog #AAA837421) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cathepsin V can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the CTSV ctsv for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cathepsin V, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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