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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse lung using MBS767509 (CARS antibody) at dilution of 1:100)

Rabbit anti-Human CARS Polyclonal Antibody | anti-CARS antibody

CARS Rabbit Polyclonal

Gene Names
CARS; CARS1; CYSRS; MGC:11246
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
CARS; Polyclonal Antibody; CARS Rabbit Polyclonal; anti-CARS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
831
Applicable Applications for anti-CARS antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Immunogen
Cysteinyl-tRNA synthetase
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse lung using MBS767509 (CARS antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse lung using MBS767509 (CARS antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS767509 (CARS antibody) at dilution of 1:1500)

Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with MBS767509 (CARS antibody) at dilution of 1:1500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
833
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94,638 Da
NCBI Official Full Name
cysteine--tRNA ligase, cytoplasmic isoform c
NCBI Official Synonym Full Names
cysteinyl-tRNA synthetase
NCBI Official Symbol
CARS
NCBI Official Synonym Symbols
CARS1; CYSRS; MGC:11246
NCBI Protein Information
cysteine--tRNA ligase, cytoplasmic
UniProt Protein Name
Cysteine--tRNA ligase, cytoplasmic
Protein Family
UniProt Gene Name
CARS
UniProt Synonym Gene Names
CysRS
UniProt Entry Name
SYCC_HUMAN

NCBI Description

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Uniprot Description

CARS: a class 1 aminoacyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. Two alternatively spliced isoforms are described.

Protein type: Translation; Ligase; Oncoprotein; EC 6.1.1.16

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; cytosol

Molecular Function: ATP binding; cysteine-tRNA ligase activity; metal ion binding; protein binding; protein homodimerization activity; tRNA binding

Biological Process: cysteinyl-tRNA aminoacylation; tRNA aminoacylation for protein translation

Research Articles on CARS

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Product Notes

The CARS cars (Catalog #AAA767509) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CARS Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CARS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the CARS cars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CARS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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