Rabbit anti-Human CAPN7 Polyclonal Antibody | anti-CAPN7 antibody

CAPN7 (Calpain-7, PalB Homolog, PalBH, PALBH)

Cat. Num. AAA649262

• Gene Names: CAPN7; PALBH; CALPAIN7
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: CAPN7; Polyclonal Antibody; CAPN7 (Calpain-7; PalB Homolog; PalBH; PALBH); Anti -CAPN7 (Calpain-7; anti-CAPN7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CAPN7.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MDATALERDAVQFARLAVQRDHEGRYSEAVFYYKEAAQALIYAEMAGSSLENIQEKITEYLERVQALHSAVQSKSADPLKSKHQLDLERAHFLVTQAFDEDEKENVEDAIELYTEAVDLCLKTSYETADKVLQNKLKQLARQALDRAEALSEPLTKPVGKISSTSVKPKPPPVRAHFPLGANPFLERPQSFISPQSCDAQGQRYTAEEIEVLRTTSKINGIEYVPFMNVDLRERFAYPMPFCDRWGKLPLSPKQKTTFSKWVRPEDLTNNPTMIYTVSSFSIKQTIVSDCSFVASLAISAAYERRFNKKLITGIIYPQNKDGEPEYNPCGKYMVKLHLNGVPRKVIIDDQLPVDHKGELLCSYSNNKSELWVSLIEKAYMKVMGGYDFPGSNSNIDLHALTGWIPERIAMHSDSQTFSKDNSFRMLYQRFHKGDVLITASTGMMTEAEGEKWGLVPTHAYAVLDIREFKGLRFIQLKNPWSHLRWKGRYSENDVKNWTPELQKYLNFDPRTAQKIDNGIFWISWDDLCQYYDVIYLSWNPGLFKESTCIHSTWDAKQGPVKDAYSLANNPQYKLEVQCPQGGAAVWVLLSRHITDKDDFANNREFITMVVYKTDGKKVYYPADPPPYIDGIRINSPHYLTKIKLTTPGTHTFTLVVSQYEKQNTIHYTVRVYSACSFTFSKIPSPYTLSKRINGKWSGQSAGGCGNFQETHKNNPIYQFHIEKTGPLLIELRGPRQYSVGFEVVTVSTLGDPGPHGFLRKSSGDYRCGFCYLELENIPSGIFNIIPSTFLPKQEGPFFLDFNSIIPIKITQLQ

• Applicable Applications for anti-CAPN7 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human CAPN7, aa1-813 (NP_055111.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of CAPN7 expression in transfected 293T cell line by CAPN7 polyclonal antibody. Lane 1: CAPN7 transfected lysate (92.7kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-CAPN7 antibody

Calcium-regulated non-lysosomal thiol-protease.

Product Categories/Family for anti-CAPN7 antibody

Antibodies; Abs to Calpain

NCBI and Uniprot Product Information

• NCBI GI #: 7656959
• NCBI GeneID: 23473
• NCBI Accession #: NP_055111.1
• NCBI GenBank Nucleotide #: NM_014296.2
• UniProt Accession #: Q9Y6W3
• Molecular Weight: 92,652 Da
• NCBI Official Full Name: calpain-7
• NCBI Official Synonym Full Names: calpain 7
• NCBI Official Symbol: CAPN7
• NCBI Official Synonym Symbols: PALBH; CALPAIN7
• NCBI Protein Information: calpain-7; palB homolog; calpain like protease; homolog of Aspergillus Nidulans PALB
• UniProt Protein Name: Calpain-7
• Protein Family: Calpain
• UniProt Gene Name: CAPN7
• UniProt Synonym Gene Names: PALBH; PalBH
• UniProt Entry Name: CAN7_HUMAN

NCBI Description

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Calcium-regulated non-lysosomal thiol-protease

By similarity.

Catalytic activity: Broad endopeptidase specificity.

Subcellular location: Nucleus.

Tissue specificity: Ubiquitous.

Sequence similarities: Belongs to the peptidase C2 family.Contains 1 calpain catalytic domain.