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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)

Rabbit anti-Human, Mouse CAPN7 Polyclonal Antibody | anti-CAPN7 antibody

CAPN7 Antibody

Gene Names
CAPN7; PALBH; CALPAIN7
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
CAPN7; Polyclonal Antibody; CAPN7 Antibody; PALBH; CALPAIN7; anti-CAPN7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CAPN7 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.7 mg/ml (varies by lot)
Sequence Length
813
Applicable Applications for anti-CAPN7 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:50-1:200
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human calpain 7
Target Name
CAPN7
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/40.)
Related Product Information for anti-CAPN7 antibody
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
Product Categories/Family for anti-CAPN7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92,652 Da
NCBI Official Full Name
calpain-7
NCBI Official Synonym Full Names
calpain 7
NCBI Official Symbol
CAPN7
NCBI Official Synonym Symbols
PALBH; CALPAIN7
NCBI Protein Information
calpain-7
UniProt Protein Name
Calpain-7
Protein Family
UniProt Gene Name
CAPN7
UniProt Synonym Gene Names
PALBH; PalBH
UniProt Entry Name
CAN7_HUMAN

NCBI Description

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]

Uniprot Description

CAPN7: Calcium-regulated non-lysosomal thiol-protease. Belongs to the peptidase C2 family.

Protein type: Protease; EC 3.4.22.-; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p24

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding; endopeptidase activity; calcium-dependent cysteine-type endopeptidase activity

Research Articles on CAPN7

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Product Notes

The CAPN7 capn7 (Catalog #AAA9402566) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPN7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CAPN7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CAPN7 capn7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPN7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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