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Western Blot (WB) (Western blot analysis of CALCOCO2 expression in mouse pancreas (A), rat skeletal muscle (B) whole cell lysates.)

Rabbit anti-Human CALCOCO2 Polyclonal Antibody | anti-CALCOCO2 antibody

Anti-CALCOCO2 Antibody

Gene Names
CALCOCO2; NDP52
Reactivity
Human
Applications
Western Blot
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
CALCOCO2; Polyclonal Antibody; Anti-CALCOCO2 Antibody; NDP52; Calcium-binding and coiled-coil domain-containing protein 2; Antigen nuclear dot 52 kDa protein; Nuclear domain 10 protein NDP52; Nuclear domain 10 protein 52; Nuclear dot protein 52; anti-CALCOCO2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CALCOCO2 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
374
Applicable Applications for anti-CALCOCO2 antibody
Western Blot (WB)
Application Notes
WB: 1/500 - 1/2000
Immunogen
Recombinant full length protein of human CALCOCO2
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of CALCOCO2 expression in mouse pancreas (A), rat skeletal muscle (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of CALCOCO2 expression in mouse pancreas (A), rat skeletal muscle (B) whole cell lysates.)
Related Product Information for anti-CALCOCO2 antibody
Rabbit polyclonal antibody to CALCOCO2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,669 Da
NCBI Official Full Name
calcium-binding and coiled-coil domain-containing protein 2 isoform 1
NCBI Official Synonym Full Names
calcium binding and coiled-coil domain 2
NCBI Official Symbol
CALCOCO2
NCBI Official Synonym Symbols
NDP52
NCBI Protein Information
calcium-binding and coiled-coil domain-containing protein 2
UniProt Protein Name
Calcium-binding and coiled-coil domain-containing protein 2
UniProt Gene Name
CALCOCO2
UniProt Synonym Gene Names
; Nuclear domain 10 protein 52
UniProt Entry Name
CACO2_HUMAN

NCBI Description

This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Uniprot Description

CALCOCO2: May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion. Part of a complex consisting of CALCOCO2, TAX1BP1 and MYO6. Interacts with GEMIN4. Expressed in all tissues tested with highest expression in skeletal muscle and lowest in brain.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: autophagic vacuole; cytoplasm; cytoplasmic vesicle; cytoskeleton; intracellular membrane-bound organelle; membrane; nucleus; perinuclear region of cytoplasm

Molecular Function: protein binding; protein homodimerization activity

Biological Process: viral reproduction

Research Articles on CALCOCO2

Similar Products

Product Notes

The CALCOCO2 calcoco2 (Catalog #AAA8245795) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CALCOCO2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CALCOCO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1/500 - 1/2000. Researchers should empirically determine the suitability of the CALCOCO2 calcoco2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CALCOCO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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