Western Blot (WB)
(Western blot analysis: Lane 1: Rat Brain Lysate, Lane 2: Mouse Brain Lysate.)
Rabbit Calcineurin A Polyclonal Antibody | anti-PPP3CB antibody
Calcineurin A polyclonal antibody
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~61kDa by Western blot.
Western Blot (WB)
(Western blot analysis: Lane 1: Rat Brain Lysate, Lane 2: Mouse Brain Lysate.)
Western Blot (WB)
(Western blot analysis: Lane 1: Rat Brain Lysate, Lane 2: Mouse Brain Lysate.)
NCBI and Uniprot Product Information
Uniprot Description
PPP3CB: a calmodulin-dependent Ser/Thr phosphatase also known calcineurin A beta. Involved in a wide range of biologic activities, acting as a Ca(2 )-dependent modifier of phosphorylation status. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively.
Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 10q22.2
Cellular Component: calcineurin complex; cytosol; nucleoplasm; plasma membrane; T-tubule; Z disc
Molecular Function: calcium ion binding; calmodulin binding; calmodulin-dependent protein phosphatase activity; drug binding; enzyme binding; protein binding; protein dimerization activity; protein phosphatase 2B binding; protein serine/threonine phosphatase activity
Biological Process: axon extension; calcineurin-NFAT signaling pathway; calcium ion-dependent exocytosis; dephosphorylation; heart development; innate immune response; learning; locomotion during locomotory behavior; lymphangiogenesis; memory; negative regulation of T cell mediated cytotoxicity; positive regulation of NFAT protein import into nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid dephosphorylation; protein amino acid phosphorylation; regulation of insulin secretion; regulation of synaptic plasticity; response to cytokine stimulus; signal transduction; social behavior; stimulatory C-type lectin receptor signaling pathway; T cell activation; T cell differentiation; T cell homeostasis; T cell proliferation
Research Articles on PPP3CB
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Product Notes
The PPP3CB ppp3cb (Catalog #AAA565194) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Calcineurin A polyclonal antibody reacts with Human, Mouse, Rat, Bovine, Chicken, Dog, Drosophila, Hamster, Monkey, Porcine, Rabbit, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Calcineurin A can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). Western Blot (1:1,000, ECL) Suggested dilutions/conditions may not be available for all applications. Detects a band of ~61kDa by Western blot. Researchers should empirically determine the suitability of the PPP3CB ppp3cb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcineurin A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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