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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7051805 at dilution of 1:100)

Rabbit anti-Human CADM3 Polyclonal Antibody | anti-CADM3 antibody

CADM3 Antibody

Gene Names
CADM3; BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
CADM3; Polyclonal Antibody; CADM3 Antibody; Cell adhesion molecule 3; Brain immunoglobulin receptor; Immunoglobulin superfamily member 4B; IgSF4B; Nectin-like protein 1; NECL-1; Synaptic cell adhesion molecule 3; SynCAM3; TSLC1-like protein 1; TSLL1; IGSF4B; NECL1; SYNCAM3; UNQ225/PRO258; anti-CADM3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
398
Applicable Applications for anti-CADM3 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:20-1:200
IF: 1:50-1:200
Immunogen
Recombinant Human Cell adhesion molecule 3 protein (140-328AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7051805 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7051805 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of A549 cells using MBS7051805 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of A549 cells using MBS7051805 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Western Blot (WB)

(Western BlotPositive WB detected in: Rat stomach tissue,Mouse kidney tissueAll lanes: CADM3 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 44,48,39 KDaObserved band size: 44 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: Rat stomach tissue,Mouse kidney tissueAll lanes: CADM3 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 44,48,39 KDaObserved band size: 44 KDa)
Related Product Information for anti-CADM3 antibody
Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,326 Da
NCBI Official Full Name
cell adhesion molecule 3 isoform 2
NCBI Official Synonym Full Names
cell adhesion molecule 3
NCBI Official Symbol
CADM3
NCBI Official Synonym Symbols
BIgR; NECL1; TSLL1; IGSF4B; Necl-1; synCAM3
NCBI Protein Information
cell adhesion molecule 3
UniProt Protein Name
Cell adhesion molecule 3
Protein Family
UniProt Gene Name
CADM3
UniProt Synonym Gene Names
IGSF4B; NECL1; SYNCAM3; TSLL1; IgSF4B; NECL-1; SynCAM3; TSLL1

NCBI Description

The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]

Uniprot Description

CADM3: Involved in the cell-cell adhesion. Has both calcium- independent homophilic cell-cell adhesion activity and calcium- independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. Belongs to the nectin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: cell-cell adherens junction; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function: cell adhesion molecule binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion

Research Articles on CADM3

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Product Notes

The CADM3 cadm3 (Catalog #AAA7051805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CADM3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CADM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the CADM3 cadm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CADM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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