Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SNRNP70 antibody.)
Rabbit SNRNP70 Polyclonal Antibody | anti-SNRNP70 antibody
SNRNP70 (U1 Small Nuclear Ribonucleoprotein 70kD, RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K) (HRP)
Gene Names
SNRNP70; RPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by affinity chromatography.
Synonyms
SNRNP70; Polyclonal Antibody; SNRNP70 (U1 Small Nuclear Ribonucleoprotein 70kD; RPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K) (HRP); anti-SNRNP70 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes SNRNP70. Species Crossreactivity: human, mouse, rat
Purity/Purification
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-SNRNP70 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Applications are based on unconjugated antibody.
Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to human SNRNP70.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SNRNP70 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SNRNP70 antibody.)
Product Categories/Family for anti-SNRNP70 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,191 Da
NCBI Official Full Name
U1 small nuclear ribonucleoprotein 70 kDa isoform 2
NCBI Official Synonym Full Names
small nuclear ribonucleoprotein 70kDa (U1)
NCBI Official Symbol
SNRNP70
NCBI Official Synonym Symbols
RPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K
NCBI Protein Information
U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa
UniProt Protein Name
U1 small nuclear ribonucleoprotein 70 kDa
Protein Family
UniProt Gene Name
SNRNP70
UniProt Synonym Gene Names
RNPU1Z; RPU1; SNRP70; U1AP1; U1 snRNP 70 kDa; U1-70K; snRNP70
UniProt Entry Name
RU17_HUMAN
Uniprot Description
snRNP 70: mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Participates in pre-mRNA splicing and exonic splicing complexes. A major ribonucleoprotein antigen recognized by the sera from patients with autoimmune diseases, such as systemic lupus erythematosus. Four alternatively spliced human isoforms have been described. The truncated isoforms (2-4) cannot bind U1-snRNA.
Protein type: RNA-binding; RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: nucleoplasm; spliceosome; nuclear speck; snRNP U1; nucleus
Molecular Function: protein binding; RNA binding; nucleotide binding
Biological Process: nuclear mRNA splicing, via spliceosome; positive regulation of nuclear mRNA splicing, via spliceosome; regulation of RNA splicing; RNA splicing; gene expression; mRNA processing
Research Articles on SNRNP70
Similar Products
Product Notes
The SNRNP70 snrnp70 (Catalog #AAA6438468) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNRNP70 (U1 Small Nuclear Ribonucleoprotein 70kD, RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K) (HRP) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SNRNP70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SNRNP70 snrnp70 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNRNP70, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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