Immunohistochemistry (IHC)
(Anti-CACNG8 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Mouse, Human CACNG8 Polyclonal Antibody | anti-CACNG8 antibody
Anti-CACNG8 Antibody (aa97-127) IHC-plus
WB (1:1000)
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Anti-CACNG8 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-CACNG8 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Western Blot (WB)
(CACNG8 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The CACNG8 antibody detected the CACNG8 protein (arrow).)
Western Blot (WB)
(CACNG8 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The CACNG8 antibody detected the CACNG8 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non-AUG (CUG) start codon. [provided by RefSeq, Dec 2010]
Uniprot Description
CACNG8: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, calcium
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: cell junction; plasma membrane; postsynaptic density; postsynaptic membrane; voltage-gated calcium channel complex
Molecular Function: channel regulator activity; voltage-gated calcium channel activity
Biological Process: calcium ion transport; synaptic transmission; transmission of nerve impulse
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Product Notes
The CACNG8 cacng8 (Catalog #AAA249565) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CACNG8 Antibody (aa97-127) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CACNG8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:10 - 1:100) WB (1:1000). Researchers should empirically determine the suitability of the CACNG8 cacng8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CACNG8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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