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Western Blot (WB) (CACNB1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CACNB1 antibody detected the CACNB1 protein (arrow).)

Rabbit anti-Human CACNB1 Polyclonal Antibody | anti-CACNB1 antibody

CACNB1, CT (CACNB1, CACNLB1, Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage-dependent subunit beta 1) (Biotin)

Gene Names
CACNB1; CAB1; CCHLB1; CACNLB1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CACNB1; Polyclonal Antibody; CT (CACNB1; CACNLB1; Voltage-dependent L-type calcium channel subunit beta-1; Calcium channel voltage-dependent subunit beta 1) (Biotin); Calcium channel voltage-dependent subunit beta 1; anti-CACNB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Sequence Length
523
Applicable Applications for anti-CACNB1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
CACNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-572 amino acids from the C-terminal region of human CACNB1.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CACNB1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CACNB1 antibody detected the CACNB1 protein (arrow).)

Western Blot (WB) (CACNB1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CACNB1 antibody detected the CACNB1 protein (arrow).)
Related Product Information for anti-CACNB1 antibody
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Product Categories/Family for anti-CACNB1 antibody
References
Jangsangthong, W., et al. Pflugers Arch. 459(3):399-411(2010). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Lim, J., et al. Cell 125(4):801-814(2006). Foell, J.D., et al. Physiol. Genomics 17(2):183-200(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
782
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit beta-1 isoform 2
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit beta 1
NCBI Official Symbol
CACNB1
NCBI Official Synonym Symbols
CAB1; CCHLB1; CACNLB1
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-1
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit beta-1
UniProt Gene Name
CACNB1
UniProt Synonym Gene Names
CACNLB1; CAB1
UniProt Entry Name
CACB1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, calcium

Chromosomal Location of Human Ortholog: 17q21-q22

Cellular Component: sarcoplasmic reticulum; T-tubule; voltage-gated calcium channel complex

Molecular Function: voltage-gated calcium channel activity; high voltage-gated calcium channel activity

Biological Process: synaptic transmission; axon guidance; transport; protein targeting to membrane; neuromuscular junction development

Research Articles on CACNB1

Similar Products

Product Notes

The CACNB1 cacnb1 (Catalog #AAA6280344) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CACNB1, CT (CACNB1, CACNLB1, Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage-dependent subunit beta 1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CACNB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CACNB1 cacnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CACNB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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