Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 46380(CABIN1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human CABIN1 Polyclonal Antibody | anti-CABIN1 antibody
CABIN1 Antibody
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 46380(CABIN1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 46380(CABIN1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200))
NCBI and Uniprot Product Information
NCBI Description
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
Uniprot Description
May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.
Research Articles on CABIN1
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Product Notes
The CABIN1 cabin1 (Catalog #AAA9429528) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CABIN1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CABIN1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 40-200. Researchers should empirically determine the suitability of the CABIN1 cabin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CABIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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