Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46375(C5AR1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Rabbit anti-Human C5AR1 Polyclonal Antibody | anti-C5AR1 antibody
C5AR1 Antibody
Gene Names
C5AR1; C5A; C5AR; C5R1; CD88
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
C5AR1; Polyclonal Antibody; C5AR1 Antibody; C5A; C5AR; C5R1; CD88; anti-C5AR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total C5AR1 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.2mg/ml (varies by lot)
Sequence Length
1625
Applicable Applications for anti-C5AR1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 40-200
Immunogen
Synthetic protein corresponding to residues near the C terminal of human C5AR1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46375(C5AR1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46375(C5AR1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46375(C5AR1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46375(C5AR1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Related Product Information for anti-C5AR1 antibody
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Product Categories/Family for anti-C5AR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
39,336 Da
NCBI Official Full Name
Homo sapiens complement component 5a receptor 1, mRNA
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
Protein Family
UniProt Gene Name
C5AR1
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR
Uniprot Description
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Research Articles on C5AR1
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Product Notes
The C5AR1 c5ar1 (Catalog #AAA9429523) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C5AR1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C5AR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 40-200. Researchers should empirically determine the suitability of the C5AR1 c5ar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C5AR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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