Rabbit anti-Human C21orf59 Polyclonal Antibody | anti-C21orf59 antibody
C21orf59 Antibody
IHC: 1: 25-100
SDS-Page
(Gel: 8%SDS-PAGE Lysate: 40 ¦Œg, Lane:Human testis tissue lysate Primary antibody: 46370(C21orf59 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 46370(C21orf59 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Naturally occuring readthrough transcription occurs from this locus to the downstream t-complex 10 like (TCP10L) gene. [provided by RefSeq, Apr 2017]
Uniprot Description
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (). May suppress canonical Wnt signaling activity ().
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Product Notes
The C21orf59 c21orf59 (Catalog #AAA9429518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C21orf59 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C21orf59 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1: 25-100. Researchers should empirically determine the suitability of the C21orf59 c21orf59 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C21orf59, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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