Western Blot (WB)
(Western Blot analysis of extracts of mouse bone marrow, using C1R antibody.)
Rabbit C1R Polyclonal Antibody | anti-C1R antibody
C1R Polyclonal Antibody
IF: 1:50-1:200
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of mouse bone marrow, using C1R antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of mouse bone marrow, using C1R antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]
Uniprot Description
C1R: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. Belongs to the peptidase S1 family.
Protein type: EC 3.4.21.41; Protease
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: extracellular region
Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; calcium ion binding
Biological Process: innate immune response; immune response; proteolysis; complement activation, classical pathway; complement activation
Disease: Complement Component C1r/c1s Deficiency
Research Articles on C1R
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Product Notes
The C1R c1r (Catalog #AAA3011789) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C1R Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's C1R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the C1R c1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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