Rabbit anti-Human C1R Polyclonal Antibody | anti-C1R antibody

C1R (Complement C1r Subcomponent, Complement Component 1 Subcomponent r) (PE)

Cat. Num. AAA6371650

• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: C1R; Polyclonal Antibody; C1R (Complement C1r Subcomponent; Complement Component 1 Subcomponent r) (PE); anti-C1R antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human C1R.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-C1R antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human C1R, aa1-705 (NP_001724.3).
• Immunogen Sequence: MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(C1R rabbit polyclonal antibody. Western Blot analysis of C1R expression in human kidney.)

Western Blot (WB)

(Western Blot analysis of C1R expression in transfected 293T cell line by C1R polyclonal antibody. Lane 1: C1R transfected lysate (80.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-C1R antibody

C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.

Product Categories/Family for anti-C1R antibody

Antibodies; Complement

NCBI and Uniprot Product Information

• NCBI GI #: 66347875
• NCBI GeneID: 715
• NCBI Accession #: NP_001724.3
• NCBI GenBank Nucleotide #: NM_001733.4
• UniProt Accession #: P00736; Q68D77; Q8J012; A6NJQ8
• Molecular Weight: 80,119 Da
• NCBI Official Full Name: complement C1r subcomponent
• NCBI Official Synonym Full Names: complement component 1, r subcomponent
• NCBI Official Symbol: C1R
• NCBI Protein Information: complement C1r subcomponent
• UniProt Protein Name: Complement C1r subcomponent
• Protein Family: Complement C1r subcomponent
• UniProt Gene Name: C1R
• UniProt Entry Name: C1R_HUMAN

Uniprot Description

C1R: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.41; Protease

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular region

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity; calcium ion binding

Biological Process: innate immune response; immune response; proteolysis; complement activation, classical pathway; complement activation

Disease: Complement Component C1r/c1s Deficiency