Rabbit anti-Human C10orf46 Polyclonal Antibody | anti-CACUL1 antibody

C10orf46 (CACUL1, CAC1, CDK2-associated and Cullin Domain-containing Protein 1, Cdk-associated Cullin1, FLJ40409, MGC33215)

Cat. Num. AAA6009372

• Gene Names: CACUL1; CAC1; C10orf46
• Reactivity: Human
• Applications: Immunoprecipitation
• Purity: Serum; Serum
• Synonyms: C10orf46; Polyclonal Antibody; C10orf46 (CACUL1; CAC1; CDK2-associated and Cullin Domain-containing Protein 1; Cdk-associated Cullin1; FLJ40409; MGC33215); Anti -C10orf46 (CACUL1; anti-CACUL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human C10orf46.
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a liquid.
• Sequence: MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKLNRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPVSQNFTAV

• Applicable Applications for anti-CACUL1 antibody: Immunoprecipitation (IP)
• Application Notes: Suitable for use in Immunoprecipitation.
• Immunogen: Full length human C10orf46, aa1-303 (AAH38294.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunoprecipitation (IP)

(Immunoprecipitation of C10orf46 transfected lysate using C10orf46 rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with C10orf46 mouse polyclonal antibody.)

Related Product Information for anti-CACUL1 antibody

Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition.

Product Categories/Family for anti-CACUL1 antibody

Antibodies; Abs to Cullin

NCBI and Uniprot Product Information

• NCBI GI #: 109452597
• NCBI GeneID: 143384
• NCBI Accession #: NP_722517.3
• NCBI GenBank Nucleotide #: NM_153810.4
• UniProt Accession #: Q86Y37; Q5XPL7; Q8IY11; Q8N7S4
• Molecular Weight: 41,064 Da
• NCBI Official Full Name: CDK2-associated and cullin domain-containing protein 1
• NCBI Official Synonym Full Names: CDK2-associated, cullin domain 1
• NCBI Official Symbol: CACUL1
• NCBI Official Synonym Symbols: CAC1; C10orf46
• NCBI Protein Information: CDK2-associated and cullin domain-containing protein 1; Cdk-Associated Cullin1
• UniProt Protein Name: CDK2-associated and cullin domain-containing protein 1
• Protein Family: CDK2-associated and cullin domain-containing protein
• UniProt Gene Name: CACUL1
• UniProt Synonym Gene Names: C10orf46; CAC1
• UniProt Entry Name: CACL1_HUMAN

Uniprot Description

CACUL1: Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. Belongs to the cullin family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q26.11

Cellular Component: cullin-RING ubiquitin ligase complex

Molecular Function: protein binding; ubiquitin protein ligase binding; protein kinase binding

Biological Process: ubiquitin-dependent protein catabolic process; positive regulation of protein kinase activity; positive regulation of cell proliferation; G1/S transition of mitotic cell cycle