Western Blot (WB)
(C-C motif chemokine 2 Antibody at 2ug/ml + EC109 whole cell lysate at 20 ug)
Rabbit anti-Human C-C motif chemokine 2 Polyclonal Antibody | anti-CCL2 antibody
C-C motif chemokine 2 Polyclonal Antibody
Immunohistochemistry: 1:20 - 1:200
Western Blot (WB)
(C-C motif chemokine 2 Antibody at 2ug/ml + EC109 whole cell lysate at 20 ug)
Western Blot (WB)
(C-C motif chemokine 2 Antibody at 2ug/ml + EC109 whole cell lysate at 20 ug)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human mammary gland using at dilution of 1:50.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human mammary gland using at dilution of 1:50.)
NCBI and Uniprot Product Information
Uniprot Description
CCL2: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q11.2-q12
Cellular Component: extracellular region
Molecular Function: CCR2 chemokine receptor binding; protein kinase activity; receptor binding
Biological Process: angiogenesis; astrocyte cell migration; cell adhesion; cell surface receptor linked signal transduction; cellular homeostasis; chemotaxis; cytokine and chemokine mediated signaling pathway; cytoskeleton organization and biogenesis; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; humoral immune response; inflammatory response; JAK-STAT cascade; lipopolysaccharide-mediated signaling pathway; macrophage chemotaxis; MAPKKK cascade; monocyte chemotaxis; negative regulation of neuron apoptosis; neutrophil chemotaxis; organ morphogenesis; positive regulation of GTPase activity; positive regulation of inflammatory response; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of T cell activation; protein amino acid phosphorylation; protein kinase B signaling cascade; regulation of cell shape; viral genome replication
Disease: Human Immunodeficiency Virus Type 1, Susceptibility To; Mycobacterium Tuberculosis, Susceptibility To; Neural Tube Defects
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Product Notes
The CCL2 ccl2 (Catalog #AAA9415246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C-C motif chemokine 2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C-C motif chemokine 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the CCL2 ccl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C-C motif chemokine 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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