Western Blot (WB)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS767217 (BTNL2 Antibody) at dilution of 1:600)
Rabbit BTNL2 Polyclonal Antibody | anti-BTNL2 antibody
BTNL2 Rabbit Polyclonal
Purification: Immunogen Affinity Purified
Purification: Immunogen Affinity Purified
Western Blot (WB)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS767217 (BTNL2 Antibody) at dilution of 1:600)
Western Blot (WB)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS767217 (BTNL2 Antibody) at dilution of 1:600)
NCBI and Uniprot Product Information
Uniprot Description
BTNL2: Negative regulator of T-cell proliferation. Genetic variation in BTNL2 is a cause of susceptibility to sarcoidosis type 2 (SS2). Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. A nucleotide transition affecting a splice donor site results in the use of an alternative splice site and the production of isoform 3. Individuals expressing isoform 3 have a higher risk for sarcoidosis. Belongs to the immunoglobulin superfamily. BTN/MOG family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: integral to membrane
Disease: Sarcoidosis, Susceptibility To, 2
Research Articles on BTNL2
Similar Products
Product Notes
The BTNL2 btnl2 (Catalog #AAA767217) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BTNL2 Rabbit Polyclonal reacts with Human, Mouse; other species are not tested. Please decide the specificity by homology and may cross-react with other species as described in the data sheet. AAA Biotech's BTNL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the BTNL2 btnl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTNL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
