Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200)
Rabbit anti-Human BTN3A1/2/3 Polyclonal Antibody | anti-BTN3A1/2/3 antibody
BTN3A1/2/3 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200)
NCBI and Uniprot Product Information
NCBI Description
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]
Uniprot Description
BTN3A1: Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. Belongs to the immunoglobulin superfamily. BTN/MOG family. Homodimer. 3 isoforms of the human protein are produced by alternative splicing
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p22.2
Cellular Component: plasma membrane
Molecular Function: protein binding
Biological Process: activated T cell proliferation; cytokine secretion; T cell receptor signaling pathway
Research Articles on BTN3A1/2/3
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Product Notes
The BTN3A1/2/3 btn3a1 (Catalog #AAA9419814) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BTN3A1/2/3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BTN3A1/2/3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the BTN3A1/2/3 btn3a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTN3A1/2/3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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