Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using BSPRY Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human BSPRY Polyclonal Antibody | anti-BSPRY antibody
BSPRY Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
BSPRY; Polyclonal Antibody; BSPRY Antibody; anti-BSPRY antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total BSPRY protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.9mg/ml (varies by lot)
Sequence Length
407
Applicable Applications for anti-BSPRY antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1: 20-100
Immunogen
Synthetic peptide of human BSPRY
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using BSPRY Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using BSPRY Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-BSPRY antibody
BSPRY (B-box and SPRY domain containing) is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Product Categories/Family for anti-BSPRY antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,413 Da
NCBI Official Full Name
B box and SPRY domain-containing protein isoform 1
NCBI Official Synonym Full Names
B-box and SPRY domain containing
NCBI Official Symbol
BSPRY
NCBI Protein Information
B box and SPRY domain-containing protein
UniProt Protein Name
B box and SPRY domain-containing protein
Protein Family
UniProt Gene Name
BSPRY
UniProt Entry Name
BSPRY_HUMAN
Uniprot Description
BSPRY: May regulate epithelial calcium transport by inhibiting TRPV5 activity. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 9q32
Research Articles on BSPRY
Similar Products
Product Notes
The BSPRY bspry (Catalog #AAA9417415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BSPRY Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BSPRY can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the BSPRY bspry for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BSPRY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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