Immunohistochemistry (IHC)
(BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, Mouse BRUNOL6 Polyclonal Antibody | anti-CELF6 antibody
BRUNOL6, NT (CELF6, BRUNOL6, CUGBP Elav-like family member 6, Bruno-like protein 6, CUG-BP- and ETR-3-like factor 6, RNA-binding protein BRUNOL-6)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Immunohistochemistry (IHC)
(BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(BRUNOL6 Antibody (N-term) western blot analysis in mouse kidney,liver tissue lysates (35ug/lane).This demonstrates the BRUNOL6 antibody detected the BRUNOL6 protein (arrow).)
Western Blot (WB)
(BRUNOL6 Antibody (N-term) western blot analysis in mouse kidney,liver tissue lysates (35ug/lane).This demonstrates the BRUNOL6 antibody detected the BRUNOL6 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Uniprot Description
CELF6: RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA. Belongs to the CELF/BRUNOL family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA splicing; RNA-binding; RNA processing
Chromosomal Location of Human Ortholog: 15q24
Cellular Component: cytoplasm; nucleus
Molecular Function: RNA binding; nucleotide binding
Biological Process: mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on CELF6
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Product Notes
The CELF6 celf6 (Catalog #AAA6009863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRUNOL6, NT (CELF6, BRUNOL6, CUGBP Elav-like family member 6, Bruno-like protein 6, CUG-BP- and ETR-3-like factor 6, RNA-binding protein BRUNOL-6) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BRUNOL6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the CELF6 celf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRUNOL6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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