Western Blot (WB)
(Anti-BRP44L Antibody (C-term)at 1:2000 dilution + human liver lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human BRP44L Polyclonal Antibody | anti-MPC1 antibody
BRP44L Antibody (C-term)
Western Blot (WB)
(Anti-BRP44L Antibody (C-term)at 1:2000 dilution + human liver lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-BRP44L Antibody (C-term)at 1:2000 dilution + human liver lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Yu W.-Q.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012]
Uniprot Description
BRP44L: Mediates the uptake of pyruvate into mitochondria. Defects in MPC1 are the cause of mitochondrial pyruvate carrier deficiency (MPYCD). An autosomal recessive metabolic disorder characterized by severely delayed psychomotor development, mild dysmorphic features, hepatomegaly, marked metabolic acidosis, hyperlactacidemia with normal lactate/pyruvate, and encephalopathy. Some patients have epilepsy and peripheral neuropathy. Belongs to the mitochondrial pyruvate carrier (MPC) family.
Protein type: Membrane protein, multi-pass; Mitochondrial
Chromosomal Location of Human Ortholog: 6q27
Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane
Molecular Function: pyruvate transmembrane transporter activity
Biological Process: cellular metabolic process; mitochondrial pyruvate transport; pyruvate metabolic process
Disease: Mitochondrial Pyruvate Carrier Deficiency
Research Articles on MPC1
Similar Products
Product Notes
The MPC1 mpc1 (Catalog #AAA9213816) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRP44L Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BRP44L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the MPC1 mpc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRP44L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
