Western Blot (WB)
(Western blot analysis of BRAL1 in human brain tissue lysate with BRAL1 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit BRAL1 Polyclonal Antibody | anti-BRAL1 antibody
BRAL1 Antibody
Gene Names
HAPLN2; BRAL1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
BRAL1; Polyclonal Antibody; BRAL1 Antibody; Brain link protein-1; hyaluronan and proteoglycan link protein 2; HAPLN2; anti-BRAL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
340
Applicable Applications for anti-BRAL1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 12 amino acid peptide from near the center of human BRAL1.
Target Name
BRAL1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of BRAL1 in human brain tissue lysate with BRAL1 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of BRAL1 in human brain tissue lysate with BRAL1 antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemical staining of human brain tissue using BRAL1 antibody at 2.5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemical staining of human brain tissue using BRAL1 antibody at 2.5 ug/mL.)
Related Product Information for anti-BRAL1 antibody
BRAL1 is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.
Product Categories/Family for anti-BRAL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,775 Da
NCBI Official Full Name
hyaluronan and proteoglycan link protein 2
NCBI Official Synonym Full Names
hyaluronan and proteoglycan link protein 2
NCBI Official Symbol
HAPLN2
NCBI Official Synonym Symbols
BRAL1
NCBI Protein Information
hyaluronan and proteoglycan link protein 2
UniProt Protein Name
Hyaluronan and proteoglycan link protein 2
UniProt Gene Name
HAPLN2
UniProt Synonym Gene Names
BRAL1
UniProt Entry Name
HPLN2_HUMAN
Uniprot Description
HAPLN2: Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan- associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid. Belongs to the HAPLN family.
Protein type: Secreted, signal peptide; Extracellular matrix; Secreted
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: proteinaceous extracellular matrix
Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding
Biological Process: central nervous system development; establishment of blood-nerve barrier; cell adhesion; skeletal development
Research Articles on BRAL1
Similar Products
Product Notes
The BRAL1 hapln2 (Catalog #AAA9402876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRAL1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BRAL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the BRAL1 hapln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRAL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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