Immunohistochemistry (IHC)
(Anti-BMP8B antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
Rabbit anti-Human BMP8B Polyclonal Antibody | anti-BMP8B antibody
Anti-BMP8B Antibody (aa253-302)
IF: 1:100-1:500
IHC-P: 1:50
WB: 1:500-1:1000
Immunohistochemistry (IHC)
(Anti-BMP8B antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
Immunohistochemistry (IHC)
(Anti-BMP8B antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)
Immunofluorescence (IF)
(Immunofluorescence of A549 cells, using BMP8A Antibody. The picture on the right is treated with the synthesized peptide.)
Immunofluorescence (IF)
(Immunofluorescence of A549 cells, using BMP8A Antibody. The picture on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot of extracts from COLO cells, using BMP8A Antibody. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot of extracts from COLO cells, using BMP8A Antibody. The lane on the right is treated with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
Uniprot Description
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis ().
Research Articles on BMP8B
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Product Notes
The BMP8B bmp8b (Catalog #AAA2401080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-BMP8B Antibody (aa253-302) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BMP8B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:20000 IF: 1:100-1:500 IHC-P: 1:50 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the BMP8B bmp8b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP8B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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