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Immunofluorescence (IF) (At 45 days, the bone mineralization rates of the (A) rhBMP-2/CPC and the (B) rhBMP-2/GM/CPC groups were greater than those of the (C) untreated group, and the rates of the rhBMP-2/GM/CPC group were greater than those of the rhBMP-2/CPC group. However, there were no differences in the mineralization rates among the (D) rhBMP-2/CPC, (E) rhBMP-2/GM/CPC, and (F) untreated groups at 140 days (Double fluorescent labeling; original magnification, 100X).)

Goat BMP2 + BMP4 Polyclonal Antibody | anti-BMP2 + BMP4 antibody

BMP2 + BMP4 antibody

Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
BMP2 + BMP4; Polyclonal Antibody; BMP2 + BMP4 antibody; Polyclonal BMP2 + BMP4; Anti-BMP2 + BMP4; BMP + BMP4 2; BMP2/4; Bone Morphogenetic Protein 2 + 4; BMP + BMP4 -2; BMP-2/4; anti-BMP2 + BMP4 antibody
Ordering
For Research Use Only!
Host
Goat
Clonality
Polyclonal
Isotype
IgG2a
Form/Format
0.2 um filtered and supplied in PBS with 5% trehalose.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
89
Applicable Applications for anti-BMP2 + BMP4 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
ELISA: 0.5-1.0 ug/mL
WB: 0.1 - 0.2 ug/ml
Biological Significance
There are at least 20 structurally and functionally related BMPs, which are members of the TGF-beta superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. They are also involved in embryogenesis and morphogenesis of various tissues and organs. BMPs regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. Similar to other TGF-beta family proteins, BMPs are highly conserved across animal species.
Cross-Reactivity
Human, Rat
Immunogen
BMP2/BMP4 antibody was raised in goat using recombinant human BMP-2 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF)

(At 45 days, the bone mineralization rates of the (A) rhBMP-2/CPC and the (B) rhBMP-2/GM/CPC groups were greater than those of the (C) untreated group, and the rates of the rhBMP-2/GM/CPC group were greater than those of the rhBMP-2/CPC group. However, there were no differences in the mineralization rates among the (D) rhBMP-2/CPC, (E) rhBMP-2/GM/CPC, and (F) untreated groups at 140 days (Double fluorescent labeling; original magnification, 100X).)

Immunofluorescence (IF) (At 45 days, the bone mineralization rates of the (A) rhBMP-2/CPC and the (B) rhBMP-2/GM/CPC groups were greater than those of the (C) untreated group, and the rates of the rhBMP-2/GM/CPC group were greater than those of the rhBMP-2/CPC group. However, there were no differences in the mineralization rates among the (D) rhBMP-2/CPC, (E) rhBMP-2/GM/CPC, and (F) untreated groups at 140 days (Double fluorescent labeling; original magnification, 100X).)
Related Product Information for anti-BMP2 + BMP4 antibody
Affinity purified Goat polyclonal BMP2 + BMP4 antibody
Product Categories/Family for anti-BMP2 + BMP4 antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
10,064 Da
NCBI Official Full Name
bone morphogenetic protein 2/4, partial
UniProt Protein Name
Bone morphogenetic protein 2/4
UniProt Gene Name
BMP2/4
UniProt Entry Name
Q8T5G6_ACTEQ

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Product Notes

The BMP2 + BMP4 bmp2/4 (Catalog #AAA535195) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BMP2 + BMP4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). ELISA: 0.5-1.0 ug/mL WB: 0.1 - 0.2 ug/ml. Researchers should empirically determine the suitability of the BMP2 + BMP4 bmp2/4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP2 + BMP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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