Rabbit BFAR Polyclonal Antibody | anti-BFAR antibody
BFAR Antibody
Gene Names
BFAR; BAR; RNF47
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
BFAR; Polyclonal Antibody; BFAR Antibody; BAR; Bfar; BFAR_HUMAN; Bifunctional apoptosis inhibitor; Bifunctional apoptosis regulator; RING finger protein 47; RNF47; anti-BFAR antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
BFAR Antibody detects endogenous levels of BFAR.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-BFAR antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human BFAR.
Conjugation
Unconjugated
Subunit Structure
Interacts with CASP8, BCL2 and BCL2L1 through SAM domain and also with HIP1, IFT57, ESRRBL1 and BCAP31.
Tissue Specificity
Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen.
Function
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-BFAR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,652 Da
NCBI Official Full Name
bifunctional apoptosis regulator
NCBI Official Synonym Full Names
bifunctional apoptosis regulator
NCBI Official Symbol
BFAR
NCBI Official Synonym Symbols
BAR; RNF47
NCBI Protein Information
bifunctional apoptosis regulator; RING finger protein 47; bifunctional apoptosis inhibitor
UniProt Protein Name
Bifunctional apoptosis regulator
Protein Family
UniProt Gene Name
BFAR
UniProt Synonym Gene Names
BAR; RNF47
UniProt Entry Name
BFAR_HUMAN
Uniprot Description
BFAR: Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
Protein type: Ubiquitin conjugating system; Membrane protein, multi-pass; Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 16p13.12
Cellular Component: endoplasmic reticulum membrane; membrane; integral to plasma membrane
Molecular Function: zinc ion binding; structural molecule activity
Biological Process: apoptosis; negative regulation of apoptosis
Research Articles on BFAR
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Product Notes
The BFAR bfar (Catalog #AAA9630271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BFAR Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BFAR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the BFAR bfar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BFAR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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