Rabbit anti-Human BEX1 Polyclonal Antibody | anti-BEX1 antibody
BEX1 Antibody
Gene Names
BEX1; BEX2; HBEX2; HGR74-h
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
BEX1; Polyclonal Antibody; BEX1 Antibody; BEX2; Brain expressed X linked 1; HBEX2; Protein BEX1; Reduced expression protein 3; REX 3; REX3; anti-BEX1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
BEX1 Antibody detects endogenous levels of BEX1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-BEX1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human BEX1.
Conjugation
Unconjugated
Similarity
Belongs to the BEX family.
Post Translational Modifications
Phosphorylated. Phosphorylation of Ser-102 protects it from the proteasome (By similarity).Ubiquitinated. Degraded by the proteasome (By similarity).
Subunit Structure
Interacts with neurotrophin receptor p75NTR/NGFR. Interacts with OMP (By similarity).
Tissue Specificity
Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia.
Function
Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).
Note
huttles between the cytoplasm and the nucleus.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,860 Da
NCBI Official Full Name
protein BEX1
NCBI Official Synonym Full Names
brain expressed, X-linked 1
NCBI Official Symbol
BEX1
NCBI Official Synonym Symbols
BEX2; HBEX2; HGR74-h
NCBI Protein Information
protein BEX1; brain-expressed X-linked protein 1; ovarian granulosa cell 13.0 kDa protein hGR74
UniProt Protein Name
Protein BEX1
Protein Family
UniProt Gene Name
BEX1
UniProt Entry Name
BEX1_HUMAN
Uniprot Description
BEX1: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. Belongs to the BEX family.
Protein type: Cell cycle regulation; Cell development/differentiation
Chromosomal Location of Human Ortholog: Xq22.1|Xq22
Cellular Component: transcription factor complex; cytoplasm; nucleus
Biological Process: nervous system development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; cell differentiation
Research Articles on BEX1
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Product Notes
The BEX1 bex1 (Catalog #AAA9630894) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BEX1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BEX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the BEX1 bex1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BEX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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