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Rabbit BEST4 Polyclonal Antibody | anti-BEST4 antibody

Bestrophin 4 Antibody BIOTIN-Conjugated

Gene Names
BEST4; VMD2L2
Reactivity
Human, Drosophila melanogaster
Applications
ELISA, Western Blot
Synonyms
BEST4; Polyclonal Antibody; Bestrophin 4 Antibody BIOTIN-Conjugated; BEST 4; Bestrophin 4; Bestrophin4; MGC126872; Vitelliform macular dystrophy 2 like 2; Vitelliform macular dystrophy 2 like protein 2; VMD2-like gene 2; VMD2L2 antibody; anti-BEST4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Drosophila melanogaster
Clonality
Polyclonal
Form/Format
BIOTIN-Conjugated
Concentration
0.75-1.20 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
473
Applicable Applications for anti-BEST4 antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes
Dot Blot: 1:2,000
ELISA: 1:2,000
Immunoprecipitation: 1:200
Western Blot: 1:500-1:1,000
Immunogen
Synthetic peptide taken within amino acid region 400-500 on human Bestrophin 4 protein.
Expression
Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.
Molecular Function
Chloride Channel
Structure
Belongs to bestrophin Family
Subcellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-BEST4 antibody
BIOTIN-Conjugated Bestrophin 4 Antibody
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,497 Da
NCBI Official Full Name
bestrophin-4
NCBI Official Synonym Full Names
bestrophin 4
NCBI Official Symbol
BEST4
NCBI Official Synonym Symbols
VMD2L2
NCBI Protein Information
bestrophin-4
UniProt Protein Name
Bestrophin-4
Protein Family
UniProt Gene Name
BEST4
UniProt Synonym Gene Names
VMD2L2
UniProt Entry Name
BEST4_HUMAN

NCBI Description

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon. [provided by RefSeq, Jul 2008]

Uniprot Description

BEST4: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.

Protein type: Membrane protein, multi-pass; Transporter, ion channel; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: integral to plasma membrane

Molecular Function: chloride channel activity

Research Articles on BEST4

Similar Products

Product Notes

The BEST4 best4 (Catalog #AAA541063) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bestrophin 4 Antibody BIOTIN-Conjugated reacts with Human, Drosophila melanogaster and may cross-react with other species as described in the data sheet. AAA Biotech's BEST4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB). Dot Blot: 1:2,000 ELISA: 1:2,000 Immunoprecipitation: 1:200 Western Blot: 1:500-1:1,000. Researchers should empirically determine the suitability of the BEST4 best4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BEST4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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