Testing Data
Rabbit anti-Human BCRP (ABCG2) Polyclonal Antibody | anti-BCRP (ABCG2) antibody
BCRP (ABCG2) Antibody
Gene Names
ABCG2; MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
Reactivity
Human
Applications
Western Blot
Purity
Immunogen affinity purified antibody
Synonyms
BCRP (ABCG2); Polyclonal Antibody; BCRP (ABCG2) Antibody; Breast Cancer Resistance Protein; BCRP1; ATP-binding cassette sub-family G member 2; ATP binding cassette sub family G (WHITE) member 2; ABCG2; Mitoxantrone resistance associated protein; MXR; MXR1; anti-BCRP (ABCG2) antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Purity/Purification
Immunogen affinity purified antibody
Form/Format
Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3, 0.05 mg Thimerosal
Lyophilized
Appearance: Solid
Lyophilized
Appearance: Solid
Sequence Length
611
Applicable Applications for anti-BCRP (ABCG2) antibody
Western Blot (WB)
Application Notes
WB: 1:1000-1:5000 of 0.5 mg/ml stock
Immunogen
Synthetic peptide corresponding to amino acids around position 160 of human ABCG2
Positive Control
WB: HeLa cells, SW620 cells, MCF-7 cells, SKOV cells, Jurkat cell
Handling
The vial should be centrifuged to collect the lyophilized solid before reconstituting
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-BCRP (ABCG2) antibody
Polyclonal antibody to detect BCRP in human samples
Background: BCRP, also called ABCG2, is encoded by the ABCG2 gene. BCRP is a well-characterized ABC-transporter (which limits uptake or mediates efflux of a wide variety of drugs, carcinogens, dietary toxins across cellular membranes). It is an ATP-dependent pump with broad substrate specificity. Significant expression has been observed in the placenta and it has been shown to have a role in protecting the fetus from xenobiotics in the maternal circulation. It plays protective roles in blocking absorption at the apical membrane of the intestine, and at the blood-testis barrier, the blood-brain barrier and the membranes of hematopoietic progenitor and other stem cells. At the apical membranes of the liver and kidney, it enhances excretion of xenobiotics. In the lactating mammary gland, it has a role on excreting vitamins such as riboflavin and biotin into milk.
Background: BCRP, also called ABCG2, is encoded by the ABCG2 gene. BCRP is a well-characterized ABC-transporter (which limits uptake or mediates efflux of a wide variety of drugs, carcinogens, dietary toxins across cellular membranes). It is an ATP-dependent pump with broad substrate specificity. Significant expression has been observed in the placenta and it has been shown to have a role in protecting the fetus from xenobiotics in the maternal circulation. It plays protective roles in blocking absorption at the apical membrane of the intestine, and at the blood-testis barrier, the blood-brain barrier and the membranes of hematopoietic progenitor and other stem cells. At the apical membranes of the liver and kidney, it enhances excretion of xenobiotics. In the lactating mammary gland, it has a role on excreting vitamins such as riboflavin and biotin into milk.
Product Categories/Family for anti-BCRP (ABCG2) antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,453 Da
NCBI Official Full Name
ATP-binding cassette sub-family G member 2 isoform 2
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
NCBI Official Symbol
ABCG2
NCBI Official Synonym Symbols
MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481
NCBI Protein Information
ATP-binding cassette sub-family G member 2
UniProt Protein Name
ATP-binding cassette sub-family G member 2
UniProt Gene Name
ABCG2
UniProt Synonym Gene Names
ABCP; BCRP; BCRP1; MXR
UniProt Entry Name
ABCG2_HUMAN
Similar Products
Product Notes
The BCRP (ABCG2) abcg2 (Catalog #AAA840353) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCRP (ABCG2) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCRP (ABCG2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:5000 of 0.5 mg/ml stock. Researchers should empirically determine the suitability of the BCRP (ABCG2) abcg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCRP (ABCG2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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