Rabbit anti-Human BCL6B Polyclonal Antibody | anti-BCL6B antibody
BCL6B Conjugated Antibody
Gene Names
BCL6B; BAZF; ZNF62; ZBTB28
Reactivity
Human
Applications
Most Applications
Synonyms
BCL6B; Polyclonal Antibody; BCL6B Conjugated Antibody; BAZF; ZNF62; ZBTB28; anti-BCL6B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total BCL6B protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-BCL6B antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthetic protein corresponding to residues near the C terminal of human BCL6B
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-BCL6B antibody
Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFB expression, thereby inhibiting NFB-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
51,531 Da
NCBI Official Full Name
Homo sapiens B-cell CLL/lymphoma 6, member B (zinc finger protein), mRNA
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 6B
NCBI Official Symbol
BCL6B
NCBI Official Synonym Symbols
BAZF; ZNF62; ZBTB28
NCBI Protein Information
B-cell CLL/lymphoma 6 member B protein
UniProt Protein Name
B-cell CLL/lymphoma 6 member B protein
Protein Family
UniProt Gene Name
BCL6B
UniProt Synonym Gene Names
BAZF; ZNF62
UniProt Entry Name
BCL6B_HUMAN
Uniprot Description
BCL6B: Acts as a sequence-specific transcriptional repressor in association with BCL6. May function in a narrow stage or be related to some events in the early B-cell development.
Protein type: DNA-binding; Transcription factor; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: nucleus
Molecular Function: metal ion binding
Biological Process: myeloid cell differentiation; negative regulation of transcription from RNA polymerase II promoter; regulation of neurogenesis
Research Articles on BCL6B
Similar Products
Product Notes
The BCL6B bcl6b (Catalog #AAA9454289) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL6B Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCL6B can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the BCL6B bcl6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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