Rabbit BCL2L14 / BCL-G Polyclonal Antibody | anti-BCL2L14 antibody

Rabbit Polyclonal to Human BCL2L14 / BCL-G

Cat. Num. AAA241254

• Gene Names: BCL2L14; BCLG
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Ion exchange Chromatography
• Synonyms: BCL2L14 / BCL-G; Polyclonal Antibody; Rabbit Polyclonal to Human BCL2L14 / BCL-G; Anti-BCL2L14 / BCL-G Antibody (C-Terminus) IHC-plus; BCL2L14; Bcl2-L-14; BCLG; BCL-G; Apoptosis regulator Bcl-G; Human BCL2L14; anti-BCL2L14 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: peptide corresponding to 15 amino acids near the C-terminus of human Bcl-G
• Purity/Purification: Ion exchange Chromatography
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 252

• Applicable Applications for anti-BCL2L14 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB (2.5 - 5 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: A peptide corresponding to 15 amino acids near the C-terminus of human Bcl-G.
• Immunogen Type: Synthetic peptide
• Immunogen: BCL2L14 / BCL-G antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bcl-G.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-BCL2L14 / Bcl G antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.)

Immunohistochemistry (IHC)

(Anti-BCL2L14 / Bcl G antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of Bcl-G in Mouse Testis cells with Bcl-G antibody at 10 ug/ml.)

Western Blot (WB)

(Western blot of Bcl-G in U937 cell lysates with Bcl-G antibody at (A) 2.5 and (B) 5 ug/ml.)

Related Product Information for anti-BCL2L14 antibody

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G.

Product Categories/Family for anti-BCL2L14 antibody

Family: Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 13540529
• NCBI GeneID: 79370
• NCBI Accession #: NP_110393.1
• NCBI GenBank Nucleotide #: NM_030766.1
• UniProt Accession #: Q9BZR8; Q96QR5; Q9BZR7; A8KAD0
• Molecular Weight: 30,948 Da
• NCBI Official Full Name: apoptosis facilitator Bcl-2-like protein 14 isoform 2
• NCBI Official Synonym Full Names: BCL2-like 14 (apoptosis facilitator)
• NCBI Official Symbol: BCL2L14
• NCBI Official Synonym Symbols: BCLG
• NCBI Protein Information: apoptosis facilitator Bcl-2-like protein 14; bcl2-L-14; apoptosis regulator BCL-G
• UniProt Protein Name: Apoptosis facilitator Bcl-2-like protein 14
• Protein Family: Apoptosis facilitator Bcl-2-like protein
• UniProt Gene Name: BCL2L14
• UniProt Synonym Gene Names: BCLG; Bcl2-L-14
• UniProt Entry Name: B2L14_HUMAN

NCBI Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]

Uniprot Description

Bcl-G: Plays a role in apoptosis. Belongs to the Bcl-2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 12p13-p12

Cellular Component: membrane; cytoplasm; endomembrane system; intracellular organelle; cytosol

Molecular Function: protein binding; protein kinase binding

Biological Process: regulation of apoptosis; apoptosis