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Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 46340(BCHE Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200))

Rabbit anti-Human BCHE Polyclonal Antibody | anti-BCHE antibody

BCHE Antibody

Gene Names
BCHE; E1; CHE1; CHE2
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
BCHE; Polyclonal Antibody; BCHE Antibody; E1; CHE1; CHE2; anti-BCHE antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total BCHE protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.4mg/ml (varies by lot)
Sequence Length
732
Applicable Applications for anti-BCHE antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 50-300
Immunogen
Synthetic protein corresponding to residues near the C terminal of human BCHE
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 46340(BCHE Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 46340(BCHE Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200))
Related Product Information for anti-BCHE antibody
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Product Categories/Family for anti-BCHE antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
590
UniProt Accession #
Molecular Weight
68,418 Da
NCBI Official Full Name
Homo sapiens butyrylcholinesterase, mRNA
NCBI Official Synonym Full Names
butyrylcholinesterase
NCBI Official Symbol
BCHE
NCBI Official Synonym Symbols
E1; CHE1; CHE2
NCBI Protein Information
cholinesterase
UniProt Protein Name
Cholinesterase
Protein Family
UniProt Gene Name
BCHE
UniProt Synonym Gene Names
CHE1

NCBI Description

This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]

Uniprot Description

Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Research Articles on BCHE

Similar Products

Product Notes

The BCHE bche (Catalog #AAA9429488) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCHE Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCHE can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 50-300. Researchers should empirically determine the suitability of the BCHE bche for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCHE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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