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Western Blot (WB) (Western Blot analysis of Mouse spleen tissue using BCAS4 Polyclonal Antibody at dilution of 1:1200)

Rabbit BCAS4 Polyclonal Antibody | anti-BCAS4 antibody

BCAS4 Polyclonal Antibody

Gene Names
BCAS4; CNOL
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
BCAS4; Polyclonal Antibody; BCAS4 Polyclonal Antibody; CNOL; anti-BCAS4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
3.2mg/mL (varies by lot)
Sequence Length
203
Applicable Applications for anti-BCAS4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human BCAS4
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Mouse spleen tissue using BCAS4 Polyclonal Antibody at dilution of 1:1200)

Western Blot (WB) (Western Blot analysis of Mouse spleen tissue using BCAS4 Polyclonal Antibody at dilution of 1:1200)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gastic cancer using BCAS4 Polyclonal Antibody at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastic cancer using BCAS4 Polyclonal Antibody at dilution of 1:50)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer using BCAS4 Polyclonal Antibody at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer using BCAS4 Polyclonal Antibody at dilution of 1:50)
Related Product Information for anti-BCAS4 antibody
The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer. The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13. 13-q13. 2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,495 Da
NCBI Official Full Name
breast carcinoma-amplified sequence 4 isoform b
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 4
NCBI Official Symbol
BCAS4
NCBI Official Synonym Symbols
CNOL
NCBI Protein Information
breast carcinoma-amplified sequence 4; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 4/3 fusion protein
UniProt Protein Name
Breast carcinoma-amplified sequence 4
UniProt Gene Name
BCAS4
UniProt Entry Name
BCAS4_HUMAN

Uniprot Description

BCAS3: A chromosomal aberration involving BCAS3 has been found in some breast carcinoma cell lines. Translocation t(17;20)(q23;q13) with BCAS4. Belongs to the WD repeat BCAS3 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Oncoprotein

Chromosomal Location of Human Ortholog: 17q23

Cellular Component: intermediate filament cytoskeleton; cytoplasmic microtubule; leading edge; cytoplasm; nucleus

Molecular Function: histone acetyltransferase binding; protein binding; histone binding; beta-tubulin binding; chromatin binding; transcription factor binding; nuclear hormone receptor binding

Biological Process: vesicle-mediated transport; response to starvation; positive regulation of catalytic activity; positive regulation of filopodium formation; microtubule organizing center organization and biogenesis; transcription, DNA-dependent; negative regulation of focal adhesion formation; positive regulation of transcription from RNA polymerase II promoter; lumen formation; angiogenesis; Golgi organization and biogenesis

Research Articles on BCAS4

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Product Notes

The BCAS4 bcas4 (Catalog #AAA2517859) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCAS4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BCAS4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the BCAS4 bcas4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCAS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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