Western Blot (WB)
(Western blot analysis of BCAS1 in human lung tissue lysate with BCAS1 antibody at 1 ug/mL.)
Rabbit anti-Human BCAS1 Polyclonal Antibody | anti-BCAS1 antibody
BCAS1 Antibody
Gene Names
BCAS1; AIBC1; NABC1
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
BCAS1; Polyclonal Antibody; BCAS1 Antibody; Breast carcinoma amplified sequence 1; AIBC1; NABC1; anti-BCAS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
629
Applicable Applications for anti-BCAS1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide near the carboxy terminus of human BCAS1.
Target Name
BCAS1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of BCAS1 in human lung tissue lysate with BCAS1 antibody at 1 ug/mL.)
Western Blot (WB)
(Western blot analysis of BCAS1 in human lung tissue lysate with BCAS1 antibody at 1 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of BCAS1 in human breast carcinoma with BCAS1 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of BCAS1 in human breast carcinoma with BCAS1 antibody at 5 ug/mL.)
Related Product Information for anti-BCAS1 antibody
BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.
Product Categories/Family for anti-BCAS1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
65,663 Da
NCBI Official Full Name
breast carcinoma amplified sequence 1, isoform CRA_b
NCBI Official Synonym Full Names
breast carcinoma amplified sequence 1
NCBI Official Symbol
BCAS1
NCBI Official Synonym Symbols
AIBC1; NABC1
NCBI Protein Information
breast carcinoma-amplified sequence 1
UniProt Protein Name
Breast carcinoma-amplified sequence 1
Protein Family
UniProt Gene Name
BCAS1
UniProt Synonym Gene Names
AIBC1; NABC1
UniProt Entry Name
BCAS1_HUMAN
NCBI Description
This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Jul 2008]
Uniprot Description
BCAS1: 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 20q13.2
Cellular Component: cytoplasm
Research Articles on BCAS1
Similar Products
Product Notes
The BCAS1 bcas1 (Catalog #AAA9404483) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCAS1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCAS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the BCAS1 bcas1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCAS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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