Rabbit BATF3 Polyclonal Antibody | anti-BATF3 antibody
BATF3 Rabbit pAb
IHC-p: 1:100-1:300.
ELISA: 1/10000.
Not yet tested in other applications.
Western Blot (WB)
(Western blot analysis of mouse-lung mousespleen lysis using BATF3 antibody. Antibody was diluted at 1:2000. Secondary Antibody was diluted at 1:20000. Cells nucleus extracted by Cytoplasmic and Nuclear Fraction kit.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin embedded human breast-cancer, antibody was diluted at 1:200.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffinembedded human breast-cancer, antibody was diluted at 1:200.)
Basic leucine zipper ATF-like transcription factor 3(BATF3) Homo sapiens This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription. [provided by RefSeq, Feb 2009].
Function:
Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12-Otetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities., similarity: Belongs to the bZIP family., similarity: Contains 1 bZIP domain., subunit: Interacts with JUN.
NCBI and Uniprot Product Information
Observed Band: 15
NCBI Description
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
Uniprot Description
AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
Research Articles on BATF3
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Product Notes
The BATF3 batf3 (Catalog #AAA8540336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BATF3 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BATF3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC-p) Paraffin, Immunofluorescence-paraffin section (IF-p), ELISA (EIA). WB: 1/500-1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. Researchers should empirically determine the suitability of the BATF3 batf3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BATF3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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