Western Blot (WB)
(Western Blot analysis of B3GNT5 expression in transfected 293T cell line by B3GNT5 polyclonal antibody. Lane 1: B3GNT5 transfected lysate (41.58kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human B3GNT5 Polyclonal Antibody | anti-B3GNT5 antibody
B3GNT5 (Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide Synthase, Lc(3)Cer Synthase, Lc3 Synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltra
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of B3GNT5 expression in transfected 293T cell line by B3GNT5 polyclonal antibody. Lane 1: B3GNT5 transfected lysate (41.58kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of B3GNT5 expression in transfected 293T cell line by B3GNT5 polyclonal antibody. Lane 1: B3GNT5 transfected lysate (41.58kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. [provided by RefSeq, Jul 2008]
Uniprot Description
B3GNT5: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development. Belongs to the glycosyltransferase 31 family.
Protein type: Membrane protein, integral; EC 2.4.1.206; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase
Chromosomal Location of Human Ortholog: 3q28
Cellular Component: Golgi membrane; integral to membrane; intracellular
Molecular Function: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity; galactosyltransferase activity; beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; central nervous system development; O-glycan processing; glycolipid biosynthetic process; protein amino acid glycosylation; post-translational protein modification
Research Articles on B3GNT5
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Product Notes
The B3GNT5 b3gnt5 (Catalog #AAA6000489) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The B3GNT5 (Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide Synthase, Lc(3)Cer Synthase, Lc3 Synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltra reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B3GNT5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the B3GNT5 b3gnt5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRMLVSGRRV KKWQLIIQLF ATCFLASLMF FWEPIDNHIV SHMKSYSYRY LINSYDFVND TLSLKHTSAG PRYQYLINHK EKCQAQDVLL LLFVKTAPEN YDRRSGIRRT WGNENYVRSQ LNANIKTLFA LGTPNPLEGE ELQRKLAWED QRYNDIIQQD FVDSFYNLTL KLLMQFSWAN TYCPHAKFLM TADDDIFIHM PNLIEYLQSL EQIGVQDFWI GRVHRGAPPI RDKSSKYYVS YEMYQWPAYP DYTAGAAYVI SGDVAAKVYE ASQTLNSSLY IDDVFMGLCA NKIGIVPQDH VFFSGEGKTP YHPCIYEKMM TSHGHLEDLQ DLWKNATDPK VKTISKGFFG QIYCRLMKII LLCKISYVDT YPCRAAFI. It is sometimes possible for the material contained within the vial of "B3GNT5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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