Western Blot (WB)
(AVPR1B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AVPR1B antibody detected the AVPR1B protein (arrow).)
Rabbit anti-Human AVPR1B Polyclonal Antibody | anti-AVPR1B antibody
AVPR1B Antibody (C-term)
Western Blot (WB)
(AVPR1B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AVPR1B antibody detected the AVPR1B protein (arrow).)
Western Blot (WB)
(AVPR1B Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AVPR1B antibody detected the AVPR1B protein (arrow).)
arginine vasopressin. This receptor belongs to the subfamily of
G-protein coupled receptors which includes AVPR1A, V2R and OXT
receptors. Its activity is mediated by G proteins which stimulate a
phosphatidylinositol-calcium second messenger system. The receptor
is primarily located in the anterior pituitary, where it stimulates
ACTH release. It is expressed at high levels in ACTH-secreting
pituitary adenomas as well as in bronchial carcinoids responsible
for the ectopic ACTH syndrome. A spliced antisense transcript of
this gene has been reported but its function is not known.
Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
van West, D., et al. Psychiatr. Genet. 19(2):102-103(2009)
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
Uniprot Description
AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: integral to plasma membrane; plasma membrane; endosome
Molecular Function: protein kinase C binding; peptide binding; vasopressin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; cellular response to hormone stimulus
Research Articles on AVPR1B
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Product Notes
The AVPR1B avpr1b (Catalog #AAA9208894) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 289-317. The AVPR1B Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AVPR1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AVPR1B avpr1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AVPR1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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