Rabbit anti-Virus Avian Influenza A H7N9 Hemagglutinin Polyclonal Antibody | anti-HA antibody

Avian Influenza A H7N9 Hemagglutinin Antibody

Cat. Num. AAA153697

• Reactivity: Virus
• Applications: ELISA
• Purity: Avian Influenza A H7N9 Hemagglutinin antibody is affinity chromatography purified via peptide column.
• Synonyms: Avian Influenza A H7N9 Hemagglutinin; Polyclonal Antibody; Avian Influenza A H7N9 Hemagglutinin Antibody; hemagglutinin; anti-HA antibody

• Host: Rabbit
• Reactivity: Virus
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: virus
• Purity/Purification: Avian Influenza A H7N9 Hemagglutinin antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 560

• Applicable Applications for anti-HA antibody: ELISA (EIA)
• Application Notes: Avian Influenza A H7N9 Hemagglutinin antibody can be used for detection of Avian Influenza A H7N9 Hemagglutinin by ELISA at 1 mug/ml.
• Conjugate: Unconjugated
• Immunogen: Avian Influenza A H7N9 Hemagglutinin antibody was raised against a synthetic peptide corresponding to 11 amino acids near the center of the hemagglutinin [Influenza A virus (A/blue-winged teal/Ohio/566/2006(H7N9))] protein.
• Buffer: Avian Influenza A H7N9 Hemagglutinin Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Avian Influenza A H7N9 Hemagglutinin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Testing Data

(H7N9 Hemagglutinin antibody detects 10 ng of Influenza A virus (A/blue-winged teal/Ohio/566/2006(H7N9)) hemagglutinin peptide, and not 10 ng of Influenza A virus (A/Shanghai/02/2013(H7N9)) hemagglutinin peptide in ELISA.)

Related Product Information for anti-HA antibody

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. H7N9 bird flu is the newest atypical influenza virus infection that has just been reported since early 2013. The emergence of this new strain occurred in China and has become the present focus for possible worldwide pandemic (3).

NCBI and Uniprot Product Information

• NCBI GI #: 496493389
• UniProt Accession #: R4NN21
• Molecular Weight: 62,108 Da
• NCBI Official Full Name: hemagglutinin
• UniProt Protein Name: Hemagglutinin
• Protein Family: Protein
• UniProt Gene Name: HA
• UniProt Entry Name: R4NN21_9INFA

Uniprot Description

Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.