Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS766964 (ATPAF2 antibody) at dilution of 1:50)
Rabbit ATPAF2 Polyclonal Antibody | anti-ATPAF2 antibody
ATPAF2 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS766964 (ATPAF2 antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human colon cancer using MBS766964 (ATPAF2 antibody) at dilution of 1:50)
Western Blot (WB)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS766964 (ATPAF2 antibody) at dilution of 1:500)
Western Blot (WB)
(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS766964 (ATPAF2 antibody) at dilution of 1:500)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. This gene is located within the Smith-Magenis syndrome region on chromosome 17. An alternatively spliced transcript variant has been described, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
ATPAF2: May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase). Defects in ATPAF2 are a cause of mitochondrial complex V deficiency nuclear type 1 (MC5DN1). A mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys and elevated lactate levels in urine, plasma and cerebrospinal fluid. Belongs to the ATP12 family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: cytoplasm; mitochondrion; nuclear speck
Molecular Function: protein binding
Biological Process: proton-transporting ATP synthase complex assembly
Disease: Mitochondrial Complex V (atp Synthase) Deficiency, Nuclear Type 1
Research Articles on ATPAF2
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Product Notes
The ATPAF2 atpaf2 (Catalog #AAA766964) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATPAF2 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATPAF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ATPAF2 atpaf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATPAF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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