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Western Blot (WB) (Western blot analysis of ATP8A1 expression in mouse brain (A), rat brain (B) whole cell lysates.)

Rabbit ATP8A1 Polyclonal Antibody | anti-ATP8A1 antibody

Anti-ATP8A1 Antibody

Gene Names
ATP8A1; ATPIA; ATPP2; ATPASEII
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
ATP8A1; Polyclonal Antibody; Anti-ATP8A1 Antibody; ATPIA; Probable phospholipid-transporting ATPase IA; ATPase class I type 8A member 1; Chromaffin granule ATPase II; anti-ATP8A1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of ATP8A1 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-ATP8A1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human ATP8A1. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of ATP8A1 expression in mouse brain (A), rat brain (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of ATP8A1 expression in mouse brain (A), rat brain (B) whole cell lysates.)
Related Product Information for anti-ATP8A1 antibody
Rabbit polyclonal antibody to ATP8A1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
1164
NCBI Official Full Name
Phospholipid-transporting ATPase IA
NCBI Official Synonym Full Names
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
NCBI Official Symbol
ATP8A1
NCBI Official Synonym Symbols
ATPIA; ATPP2; ATPASEII
NCBI Protein Information
phospholipid-transporting ATPase IA; ATPase II; chromaffin granule ATPase II; aminophospholipid translocase; ATPase class I type 8A member 1; probable phospholipid-transporting ATPase IA; P4-ATPase flippase complex alpha subunit ATP8A1
UniProt Protein Name
Phospholipid-transporting ATPase IA
UniProt Gene Name
ATP8A1
UniProt Synonym Gene Names
ATPIA
UniProt Entry Name
AT8A1_HUMAN

NCBI Description

The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP8A1: May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; EC 3.6.3.1; Hydrolase; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ion channel

Chromosomal Location of Human Ortholog: 4p13

Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; plasma membrane; integral to membrane

Molecular Function: phospholipid-translocating ATPase activity; protein binding; magnesium ion binding; ATP binding; cation-transporting ATPase activity

Biological Process: phospholipid translocation; metabolic process; learning; transmembrane transport; cation transport; positive regulation of cell migration

Research Articles on ATP8A1

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Product Notes

The ATP8A1 atp8a1 (Catalog #AAA8306093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ATP8A1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATP8A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ATP8A1 atp8a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATP8A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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