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Immunohistochemistry (IHC) (Immunohistochemistry analysis of ATP7A antibody in paraffin-embedded human brain tissue.)

Rabbit ATP7A Polyclonal Antibody | anti-ATP7A antibody

ATP7A Antibody

Gene Names
ATP7A; MK; MNK; DSMAX; SMAX3
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
ATP7A; Polyclonal Antibody; ATP7A Antibody; Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein; MC1; MNK; anti-ATP7A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
ATP7A antibody detects endogenous levels of ATP7A.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
103
Applicable Applications for anti-ATP7A antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50~1:100
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human ATP7A.
Immunogen Range
591-640
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of ATP7A antibody in paraffin-embedded human brain tissue.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of ATP7A antibody in paraffin-embedded human brain tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
538
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
163 kDa
NCBI Official Full Name
copper-transporting ATPase 1 isoform 1
NCBI Official Synonym Full Names
ATPase copper transporting alpha
NCBI Official Symbol
ATP7A
NCBI Official Synonym Symbols
MK; MNK; DSMAX; SMAX3
NCBI Protein Information
copper-transporting ATPase 1
UniProt Protein Name
Copper-transporting ATPase 1
UniProt Gene Name
ATP7A
UniProt Synonym Gene Names
MC1; MNK

NCBI Description

This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]

Uniprot Description

May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

Research Articles on ATP7A

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Product Notes

The ATP7A atp7a (Catalog #AAA9508724) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATP7A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATP7A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the ATP7A atp7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATP7A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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