Rabbit anti-Rat ATP5G3 Polyclonal Antibody | anti-ATP5G3 antibody

ATP5G3 (ATP Synthase F(0) Complex Subunit C3, Mitochondrial, ATP Synthase lipid-Binding Protein, ATP Synthase proteolipid P3, ATP Synthase proton-transporting Mitochondrial F(0) Complex Subunit C3, ATPase Protein 9, ATPase Subunit c, ATP5G3) (MaxLight 650

Cat. Num. AAA6454344

• Gene Names: ATP5G3; P3
• Reactivity: Rat
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ATP5G3; Polyclonal Antibody; ATP5G3 (ATP Synthase F(0) Complex Subunit C3; Mitochondrial; ATP Synthase lipid-Binding Protein; ATP Synthase proteolipid P3; ATP Synthase proton-transporting Mitochondrial F(0) Complex Subunit C3; ATPase Protein 9; ATPase Subunit c; ATP5G3) (MaxLight 650; anti-ATP5G3 antibody

• Host: Rabbit
• Reactivity: Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes rat ATP5G3. Species Crossreactivity: rat
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

• Applicable Applications for anti-ATP5G3 antibody: Western Blot (WB)
• Application Notes: WB: 1:2000; Applications are based on unconjugated antibody.
• Immunogen: KLH conjugated synthetic peptide corresponding to aa12-42 from human ATP5G3.
• Conjugate: MaxLight650
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-ATP5G3 antibody

Antibodies; Enzymes; Synthase

References

Yan W.L., et al. Genomics 24:375-377(1994). Ota T., et al. Nat. Genet. 36:40-45(2004). Hillier L.W., et al. Nature 434:724-731(2005). Mural R.J., et al. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

• NCBI GI #: 50659074
• NCBI GeneID: 518
• NCBI Accession #: NP_001002258.1
• NCBI GenBank Nucleotide #: NM_001002258.4
• UniProt Accession #: P48201; Q4ZFX7; B2R4Z0; D3DPF0
• Molecular Weight: 14,693 Da
• NCBI Official Full Name: ATP synthase lipid-binding protein, mitochondrial isoform A
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
• NCBI Official Symbol: ATP5G3
• NCBI Official Synonym Symbols: P3
• NCBI Protein Information: ATP synthase lipid-binding protein, mitochondrial; ATPase protein 9; ATPase subunit C; ATP synthase subunit 9; ATP synthase proteolipid P3; ATP synthase, mitochondrial, C subunit-3; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subu
• UniProt Protein Name: ATP synthase lipid-binding protein, mitochondrial
• UniProt Gene Name: ATP5G3
• UniProt Entry Name: AT5G3_HUMAN

NCBI Description

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]

Uniprot Description

ATP5G3: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family.

Protein type: Energy Metabolism - oxidative phosphorylation; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: mitochondrial outer membrane; proton-transporting ATP synthase complex, coupling factor F(o); integral to membrane; mitochondrial proton-transporting ATP synthase complex

Molecular Function: transporter activity; hydrogen ion transmembrane transporter activity; lipid binding

Biological Process: cellular metabolic process; ATP hydrolysis coupled proton transport; mitochondrial ATP synthesis coupled proton transport