Rabbit anti-Mouse, Rat ATP1A4 Polyclonal Antibody | anti-ATP1A4 antibody

ATP1A4 Polyclonal Antibody

Cat. Num. AAA2555611

• Gene Names: ATP1A4; ATP1A1; ATP1AL2
• Reactivity: Mouse, Rat
• Applications: Western Blot
• Purity: Affinity Purification
• Synonyms: ATP1A4; Polyclonal Antibody; ATP1A4 Polyclonal Antibody; ATPase Na+/K+ Transporting Subunit Alpha 4; Sodium Pump Subunit Alpha-4; ATPase Na+/K+ Transporting; Alpha Polypeptide-Like 2; Sodium/Potassium-Transporting ATPase Subunit Alpha-4; Sodium-Potassium ATPase Catalytic Subunit Alpha-4; Alpha 4 Polypeptide; Na(+)/K(+) ATPase Alpha-4 Subunit; EC 3.6.3.9; ATP1AL2; Sodium/Potassium-Transporting ATPase Alpha-4 Chain; Na+/K+ ATPase Alpha-D Polypeptide; Na; K-ATPase Subunit Alpha-C; Na+/K+ ATPase 4; Sodium Pump 4; EC 3.6.3; ATP1A1; anti-ATP1A4 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 165

• Applicable Applications for anti-ATP1A4 antibody: Western Blot (WB)
• Application Notes: WB: 1:200-1:2000
• Immunogen: Recombinant protein of human ATP1A4
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using ATP1A4 antibody.)

Related Product Information for anti-ATP1A4 antibody

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI and Uniprot Product Information

• NCBI GI #: 49249977
• NCBI GeneID: 480
• NCBI Accession #: NP_001001734.1
• NCBI GenBank Nucleotide #: NM_001001734.1
• UniProt Accession #: Q13733; Q504T2; Q7Z4I9; Q8TBN8; Q8WXA7; Q8WXH7; Q8WY13
• Molecular Weight: Calculated: 19kDa; 114kDa; Observed: 100kDa
• NCBI Official Full Name: sodium/potassium-transporting ATPase subunit alpha-4 isoform 2
• NCBI Official Synonym Full Names: ATPase Na+/K+ transporting subunit alpha 4
• NCBI Official Symbol: ATP1A4
• NCBI Official Synonym Symbols: ATP1A1; ATP1AL2
• NCBI Protein Information: sodium/potassium-transporting ATPase subunit alpha-4
• UniProt Protein Name: Sodium/potassium-transporting ATPase subunit alpha-4
• Protein Family: Sodium/potassium-transporting ATPase
• UniProt Gene Name: ATP1A4
• UniProt Synonym Gene Names: ATP1AL2; Na(+)/K(+) ATPase alpha-4 subunit

NCBI Description

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.