Goat ATNX1 Polyclonal Antibody
ATNX1 (ATX1, Ataxin 1, Ataxin-1, Spinocerebellar Ataxia Type 1 Protein, ATX1, SCA1)
Applications
ELISA
Purity
Affinity PurifiedPurified by peptide affinity chromatography.
Synonyms
ATNX1; Polyclonal Antibody; ATNX1 (ATX1; Ataxin 1; Ataxin-1; Spinocerebellar Ataxia Type 1 Protein; ATX1; SCA1); Anti -ATNX1 (ATX1; anti-ATNX1 antibody
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes ATXN1.
Species sequence homology: human, canine, porcine.
Species sequence homology: human, canine, porcine.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Purified by peptide affinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Concentration
0.5mg/mL (varies by lot)
Applicable Applications for anti-ATNX1 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: Peptide ELISA Titer: 1:64,000
Dilution: Peptide ELISA Titer: 1:64,000
Immunogen
Synthetic peptide corresponding to C-DLEVQQATHREASP, from the internal region of human ATXN1
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-ATNX1 antibody
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.
Product Categories/Family for anti-ATNX1 antibody
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Product Notes
The ATNX1 (Catalog #AAA625298) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ATNX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: Peptide ELISA Titer: 1:64,000. Researchers should empirically determine the suitability of the ATNX1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATNX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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