Rabbit ATF4 Polyclonal Antibody | anti-ATF4 antibody

Anti-ATF4 Antibody

Cat. Num. AAA415509

• Gene Names: ATF4; CREB2; TXREB; CREB-2; TAXREB67
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Purified
• Synonyms: ATF4; Polyclonal Antibody; Anti-ATF4 Antibody; anti-ATF4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ATF4 antibody detects endogenous levels of ATF4 protein. Not tested with other proteins
• Purity/Purification: Purified
• Form/Format: Liquid
• Concentration: 100ug/100ul (varies by lot)
• Sequence Length: 351

• Applicable Applications for anti-ATF4 antibody: Peptide ELISA (EIA), Western Blot (WB)
• Application Notes: Recommended dilutions:; Peptide ELISA: 1:20,000; WB: 1:200 - 1:1000; Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
• Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide
• Immunogen: Synthetic peptide conjugated to KLH
• Preparation and Storage: This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Western Blot (WB)

Related Product Information for anti-ATF4 antibody

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). This gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

References

Tsujimoto,A., Nyunoya,H., Morita,T et,al Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I

NCBI and Uniprot Product Information

• NCBI GI #: 47678299
• NCBI GeneID: 468
• UniProt Accession #: Q96AQ3; P18848
• Molecular Weight: 38,590 Da
• NCBI Official Full Name: ATF4
• NCBI Official Synonym Full Names: activating transcription factor 4
• NCBI Official Symbol: ATF4
• NCBI Official Synonym Symbols: CREB2; TXREB; CREB-2; TAXREB67
• NCBI Protein Information: cyclic AMP-dependent transcription factor ATF-4; DNA-binding protein TAXREB67; cAMP response element-binding protein 2; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; cyclic AMP-responsive element-binding protein 2; tax-responsive enhancer element B67; tax-responsive enhancer element-binding protein 67
• UniProt Protein Name: ATF4 protein
• Protein Family: Cyclic AMP-dependent transcription factor
• UniProt Gene Name: ATF4
• UniProt Entry Name: Q96AQ3_HUMAN

NCBI Description

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]