Rabbit anti-Human, Mouse ASB17 Polyclonal Antibody | anti-ASB17 antibody

ASB17, CT (ASB17, Ankyrin repeat and SOCS box protein 17) (PE)

Cat. Num. AAA6275533

• Gene Names: ASB17; Asb-17
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ASB17; Polyclonal Antibody; CT (ASB17; Ankyrin repeat and SOCS box protein 17) (PE); Ankyrin repeat and SOCS box protein 17; anti-ASB17 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-ASB17 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: ASB17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-214 amino acids from the C-terminal region of human ASB17.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunohistochemistry (IHC)

(ASB17 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ASB17 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(ASB17 Antibody (C-term) western blot analysis in mouse testis,spleen tissue lysates (35ug/lane).This demonstrates the ASB17 antibody detected the ASB17 protein (arrow).)

Related Product Information for anti-ASB17 antibody

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Product Categories/Family for anti-ASB17 antibody

Antibodies; SOCS

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005). Guo, J.H., et al. Arch. Androl. 50(3):155-161(2004). Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 27477049
• NCBI GeneID: 127247
• NCBI Accession #: NP_543144.1
• NCBI GenBank Nucleotide #: NM_080868.2
• UniProt Accession #: Q8WXJ9; Q8N0X5; B1APB8
• Molecular Weight: 34,282 Da
• NCBI Official Full Name: ankyrin repeat and SOCS box protein 17
• NCBI Official Synonym Full Names: ankyrin repeat and SOCS box containing 17
• NCBI Official Symbol: ASB17
• NCBI Official Synonym Symbols: Asb-17
• NCBI Protein Information: ankyrin repeat and SOCS box protein 17; ankyrin repeat and SOCS box-containing 17
• UniProt Protein Name: Ankyrin repeat and SOCS box protein 17
• Protein Family: Ankyrin repeat and SOCS box protein
• UniProt Gene Name: ASB17
• UniProt Synonym Gene Names: ASB-17
• UniProt Entry Name: ASB17_HUMAN

Uniprot Description

ASB17: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Chromosomal Location of Human Ortholog: 1p31.1

Biological Process: protein ubiquitination