Western Blot (WB)
(ASAP3 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).)
Rabbit ASAP3 Polyclonal Antibody | anti-ASAP3 antibody
ASAP3 Antibody (N-term)
Western Blot (WB)
(ASAP3 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).)
Western Blot (WB)
(ASAP3 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).)
Western Blot (WB)
(ASAP3 Antibody (N-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).)
Western Blot (WB)
(ASAP3 Antibody (N-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the ASAP3 antibody detected the ASAP3 protein (arrow).)
Immunohistochemistry (IHC)
(ASAP3 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ASAP3 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ASAP3 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ASAP3 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
ADP-ribosylation factor(Arf) GTPase-activating proteins that
contain additional ankyrin repeat and pleckstrin homology domains.
The Arf GAP domain of this protein catalyzes the hydrolysis of GTP
bound to Arf proteins. The encoded protein promotes cell
differentiation and migration and has been implicated in cancer
cell invasion. Alternative splicing results in multiple transcript
variants.
Ha, V.L., et al. J. Biol. Chem. 283(22):14915-14926(2008)
Fang, Z., et al. Mol. Cell Proteomics 5(8):1437-1449(2006)
Okabe, H., et al. Int. J. Oncol. 24(1):43-48(2004)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Uniprot Description
DDEFL1: Promotes cell proliferation. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; GAPs, ARF; GAPs
Chromosomal Location of Human Ortholog: 1p36.12
Cellular Component: ruffle; focal adhesion; cytoplasm
Molecular Function: zinc ion binding
Biological Process: cell migration; regulation of stress fiber formation
Research Articles on ASAP3
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Product Notes
The ASAP3 asap3 (Catalog #AAA9214574) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 26-54. The ASAP3 Antibody (N-term) reacts with Human, hamster and may cross-react with other species as described in the data sheet. AAA Biotech's ASAP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the ASAP3 asap3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASAP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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