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Western Blot (WB) (Western blot analysis of ART3 Antibody (C-term) in HL60 cell line lysates (25ug/lane). ART3(arrow) was detected using the purified Pab (4 ug/ml).)

Rabbit anti-Human ART3 Polyclonal Antibody | anti-ART3 antibody

ART3 Antibody (C-term)

Gene Names
ART3; ARTC3
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ART3; Polyclonal Antibody; ART3 Antibody (C-term); Ecto-ADP-ribosyltransferase 3; ADP-ribosyltransferase C2 and C3 toxin-like 3; ARTC3; Mono(ADP-ribosyl)transferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3; TMART; anti-ART3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ART3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-310 amino acids from the C-terminal region of human ART3.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
280-310
Sequence Length
389
Applicable Applications for anti-ART3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of ART3 Antibody (C-term) in HL60 cell line lysates (25ug/lane). ART3(arrow) was detected using the purified Pab (4 ug/ml).)

Western Blot (WB) (Western blot analysis of ART3 Antibody (C-term) in HL60 cell line lysates (25ug/lane). ART3(arrow) was detected using the purified Pab (4 ug/ml).)
Related Product Information for anti-ART3 antibody
Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein. The rodent mono-ADP-ribosyltransferase RT6 is a glycosylphosphatidylinositol (GPI)-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes. The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kD and contains a hydrophobic peptide signal at its N terminus, 3 consensus motifs specific to enzymes catalyzing ADP-ribose transfer, a hydrophobic C-terminal sequence characteristic of a GPI-anchored protein, a novel motif repeated 3 times at its C terminus, and 1 potential glycosylation site.1 The ART3 and rodent RT6 proteins share 35% amino acid identity.
Product Categories/Family for anti-ART3 antibody
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Koch-Nolte, F., et al., Genomics 39(3):370-376 (1997).
Levy, I., et al., FEBS Lett. 382(3):276-280 (1996).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
419
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43923
NCBI Official Full Name
ecto-ADP-ribosyltransferase 3 isoform a
NCBI Official Synonym Full Names
ADP-ribosyltransferase 3
NCBI Official Symbol
ART3
NCBI Official Synonym Symbols
ARTC3
NCBI Protein Information
ecto-ADP-ribosyltransferase 3
UniProt Protein Name
Ecto-ADP-ribosyltransferase 3
UniProt Gene Name
ART3
UniProt Synonym Gene Names
TMART; ARTC3
UniProt Entry Name
NAR3_HUMAN

NCBI Description

This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

ART3: an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Protein type: Transferase; Membrane protein, GPI anchor; Membrane protein, integral; EC 2.4.2.31

Chromosomal Location of Human Ortholog: 4q21.1|4p15.1-p14

Cellular Component: integral to plasma membrane

Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity

Biological Process: protein amino acid ADP-ribosylation

Research Articles on ART3

Similar Products

Product Notes

The ART3 art3 (Catalog #AAA9208009) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 280-310. The ART3 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ART3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ART3 art3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ART3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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