Western Blot (WB)
(Western Blot analysis of K562 cells with Arp3 Polyclonal Antibody.)
Rabbit Arp3 Polyclonal Antibody | anti-Arp3 antibody
Arp3 Polyclonal Antibody
Western Blot (WB)
(Western Blot analysis of K562 cells with Arp3 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of K562 cells with Arp3 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of K562 cells with Arp3 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of K562 cells with Arp3 Polyclonal Antibody.)
NCBI and Uniprot Product Information
Observed MW: 47
NCBI Description
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
Uniprot Description
Arp3: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Belongs to the actin family. ARP3 subfamily.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q14.1
Cellular Component: actin cytoskeleton; Arp2/3 protein complex; brush border; cytosol; focal adhesion; intercellular junction; lamellipodium; membrane
Molecular Function: actin filament binding; ATP binding; protein binding; structural constituent of cytoskeleton
Biological Process: asymmetric cell division; axon guidance; cell motility; cytokinesis after meiosis; ephrin receptor signaling pathway; establishment and/or maintenance of cell polarity; innate immune response; meiotic chromosome movement towards spindle pole; small GTPase mediated signal transduction; spindle localization
Research Articles on Arp3
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Product Notes
The Arp3 actr3 (Catalog #AAA2538756) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Arp3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Arp3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000, ELISA: 1:5000-1:20000. Researchers should empirically determine the suitability of the Arp3 actr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Arp3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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