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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ARMC8 Antibody) at dilution 1/60.)

Rabbit anti-Human, Mouse ARMC8 Polyclonal Antibody | anti-ARMC8 antibody

ARMC8 Antibody

Gene Names
ARMC8; GID5; VID28; S863-2; HSPC056
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ARMC8; Polyclonal Antibody; ARMC8 Antibody; GID5; VID28; S863-2; HSPC056; anti-ARMC8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-ARMC8 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:300
Immunogen
Fusion protein of human ARMC8
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ARMC8 Antibody) at dilution 1/60.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ARMC8 Antibody) at dilution 1/60.)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (ARMC8 Antibody) at dilution 1/60.)

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (ARMC8 Antibody) at dilution 1/60.)
Related Product Information for anti-ARMC8 antibody
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1, 100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Product Categories/Family for anti-ARMC8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
67,900 Da
NCBI Official Full Name
Homo sapiens armadillo repeat containing 8, mRNA
NCBI Official Synonym Full Names
armadillo repeat containing 8
NCBI Official Symbol
ARMC8
NCBI Official Synonym Symbols
GID5; VID28; S863-2; HSPC056
NCBI Protein Information
armadillo repeat-containing protein 8; GID complex subunit 5, VID28 homolog
UniProt Protein Name
Coatomer subunit epsilon
UniProt Gene Name
COPE
UniProt Synonym Gene Names
Epsilon-COP
UniProt Entry Name
COPE_HUMAN

Uniprot Description

COPE: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Belongs to the COPE family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: COPI vesicle coat; cytosol; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; nucleoplasm; transport vesicle

Molecular Function: protein binding

Biological Process: ER to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER

Research Articles on ARMC8

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Product Notes

The ARMC8 cope (Catalog #AAA9434677) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARMC8 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ARMC8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:300. Researchers should empirically determine the suitability of the ARMC8 cope for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARMC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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